This program, issued by the National Cancer Institute (NCI), invites grant applications for investigator-initiated Program Projects (P01) in any area of cancer research. P01 grants support integrated, multiproject research programs involving a number of independent investigators who share knowledge and common resources while working towards a unifying overall scientific goal. Therefore, every P01 program project proposed should have a well-defined unifying research theme.
Each Program Project application must include at least three projects. The individual projects may represent several disciplines and/or address several discrete research aspects pertinent to one or more disciplines. However, all of the projects must be relevant to the common unifying central theme or focus, and the overall objective of the entire program project. Each individual project should reflect a self-standing scientifically meritorious research effort. In addition, however, the individual projects should be clearly interrelated and synergistic so that the research ideas, efforts, and outcomes of the program as a whole will offer a distinct advantage over pursuing the individual projects separately.
This program invites multidisciplinary coordinated research programs in any of the broad areas of cancer research, including (but not limited to) studies of cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control. Basic, translational, clinical, and/or population-based studies in all of these research areas are appropriate.
Program Integration and Management (required): Program Integration and Management will be responsible for demonstrating how the coordination and integration of the individual components address the overall goals of the program more effectively than if the projects were conducted independently.
Minimum Number of Research Projects (required): Each P01 application must include at least three related research projects. The projects must share a common central theme, focus, and/or overall objective.
Shared Resource Core(s) (optional): In addition to individual research projects, applicants may propose one or more Shared Resource Cores if needed for the proposed research. Both administrative and research support cores are allowed. Each Shared Resource Core must provide support and enhance the productivity, cost-effectiveness, and/or research outcome of at least two of the proposed research projects. New cores may be proposed and/or existing institution cores may be augmented to support the proposed research.